Angewandte Naturwissenschaften, Energie-und Gebäudetechnik Prof. Dr. rer. nat. Christian Lotz, B.Sc., M.Sc.

Lehre:
- Biologie und Einführung in die Biotechnologie
- Zellbiologie
- Immunologie/Virologie/Toxikologie
- Biopharmazeutika
- Qualitätsmanagement und GMP
- Zellkulturtechnik
- Tissue Engineering
- Labor Bioanalytik

nach Vereinbarung

ORCID-ID: https://orcid.org/0000-0003-3106-1159

1. N. Knetzger, N. Ertych, T. Burgdorf, J. Beranek, M. Oelgeschlaeger, J. Waechter, A. Horchler, S. Gier, M. Windbergs, S. Fayyaz, F.A. Grimm, G. Wiora, C. Lotz. Non-invasive NAM for the detection of reversible and irreversible eye damage after chemical exposure for GHD classification purposes. Archives of Toxicology (2025). https://doi.org/10.1007/s00204-024-03940-x
2. Sarah Barbara Zwingelberg, Gizem Karabiyik, Paul Gehle, Melanie von Brandenstein, Sabina Eibichova, Christian Lotz, Florian Groeber-Becker, Daniel Kampik, Ula Jurkunas, Gerd Geerling and Gregor Lang. Advancements in Bioengineering for Descemet Membrane Endothelial Keratoplasty (DMEK). Nature Scientific Reports (2024 under Review).
3. Nicola Knetzger, Ann-Katrin Regensburger, Annika Goy, Hong Han, Johanna Theuersbacher, Ioana-Sandra Tarau, Carla Cleve, Lukas Königer, Tamara Finger, Sabina Eibichova, Malik Salman Haider, Thomas Schwarz, Jan Hansmann, Jost Hillenkamp, Daniel Kampik, Christian Lotz. From Injury to recovery investigating wound healing in a 3D tissue engineered cornea equivalent. Biomaterials (2024 under Review).
4. Weissinger, H., Knetzger, N., Cleve, C., C. Lotz. Impedance-based in vitro eye irritation testing enables the categorization of diluted chemicals. Sci Rep 14, 6216 (2024). https://doi.org/10.1038/s41598-024-56191-2
5. Schwebler, J., Fey, C., Kampik, D., Christian Lotz. Full thickness 3D in vitro conjunctiva model enables goblet cell differentiation. Sci Rep 13, 12261 (2023). https://doi.org/10.1038/s41598-023-38927-8
6. Jan Häusler, Frank A. Müller, Lenka Müller, Janet Grabow, Carla Cleve, Christian Lotz, Mona Röschlau, Patrick Bittorf, Roland Fromme, Ingrid Kiebert, Michelle Grüne, Stefan Schweizer, Sofia Dembski. Preparation of Phosphorescent Eu2+, Dy3+-Doped Strontium Aluminate Nanoparticles by Laser Vaporization for the Modification of Therapeutic Contact Lenses. Advanced Photonics Research (2022). https://doi.org/10.1002/adpr.202200013
7. F. Rohde, M. Walther, J. Wächter, N. Knetzger, C. Lotz, M. Windbergs. In-situ tear fluid dissolving nanofibers enable prolonged viscosity-enhanced dual drug delivery to the eye. Int J Pharm. (2022). https://doi.org/10.1016/j.ijpharm.2022.121513
8. Li, Pengcheng; Lee, Hee Ryung; Chandel, Shubham; Lotz, Christian; Groeber-Becker, Florian Kai; Dembski, Sofia; Ossikovski, Razvigor; Ma, Hui; Novikova, Tatiana. Analysis of tissue microstructure with Mueller microscopy: Logarithmic decomposition and Monte Carlo modeling. Journal of biomedical optics 25 (2020). https://doi.org/10.1117/1.JBO.25.1.015002
9. H.R. Lee; P.Y. L. Pengcheng; T. S. H. Yoo; C. Lotz; F. Groeber-Becker; S. Dembski; E. Garcia-Caurel; R. Ossikovski; H. Ma; T. Novikova. Digital histology with Mueller microscopy: How to mitigate an impact of tissue cut thickness fluctuations. Journal of biomedical optics 24 (2019). https://doi.org/10.1117/1.jbo.24.7.076004
10. C. Lotz; L. Kiesewetter, F.F. Schmid, J. Hansmann, H. Walles, F. Groeber-Becker. Replacing the Draize eye test: Impedance spectroscopy as a 3R method to discriminate between all GHS categories for eye irritation. Nature Scientific Reports 8 (2018). https://doi.org/10.1038/s41598-018-33118-2
11. Tobias Schmitz, Matthias Schweinlin, Robin T. Kollhoff, Lisa Engelhardt, Christian Lotz, Florian Groeber-Becker, Heike Walles, Marco Metzger, and Jan Hansmann. Nanostructured TiN-Coated Electrodes for High-Sensitivity Noninvasive Characterization of in Vitro Tissue Models. ACS applied nano materials (2018). https://pubs.acs.org/doi/abs/10.1021/acsanm.8b00345
12. R. Schmid; I. Tarau; A. Rossi; S. Leonhardt; T. Schwarz; S. Schürlein; C. Lotz; J. Hansmann. In vivo-like culture conditions in a bioreactor facilitate improved tissue quality in corneal storage. Biotechnology journal 13 (2018). https://doi.org/10.1002/biot.201700344
13. J. Lichter, U. Bock, C. Lotz, F. Groeber, B. Blömeke. Functional expression of N ‐acetyltransferase 1 in differentiated human skin keratinocytes. British Journal of Dermatology 177 (2017). https://doi.org/10.1111/bjd.15091
14. C. Lotz, F.F. Schmid, E. Oechsle, MG. Monaghan, H. Walles, F. Groeber-Becker. Cross-linked Collagen Hydrogel Matrix Resisting Contraction To Facilitate Full-Thickness Skin Equivalents. ACS applied materials & interfaces 9 (2017). https://pubs.acs.org/doi/abs/10.1021/acsami.7b04017
15. Schweinlin, Matthias; Rossi, Angela; Lodes, Nina; Lotz, Christian; Hackenberg, Stephan; Steinke, Maria; Walles, Heike; Groeber, Florian. Human barrier models for the in vitro assessment of drug delivery. Drug Delivery and Translational Research 7 (2017). https://doi.org/10.1007/s13346-016-0316-9
16. C. Lotz; F. F. Schmid; A. Rossi; S. Kurdyn; D. Kampik; B. Wever; H. Walles; F. Groeber. Alternative methods for the replacement of eye irritation testing. Alternatives to animal experimentation: ALTEX 33 (2016). https://doi.org/10.14573/altex.1508241

- Tissue Engineering

- In vitro Testsystme für Risiko- und Wirksamkeitstestung

- New approach methods